I believe The Beatles: Rock Band came the closest to being perfect. Eveything about that game was just beautifully done and the only things missing was Pro Drums, an option for Keys, and a few more Beatle songs (Hey Jude, Strawberry Fields Forever, Yesterday etc. etc.)
Lots of contenders for me: Resident Evil 2, A Link to the Past, Ocarina of time, Goldeneye, Half-Life, Diablo II, Skyrim, Alien: Isolation, Borderlands 2, Mario 64
But I gotta go with Runescape