When it got software/features I don’t use.

Fedora uses grubby to edit grub. Read documentation. Do some research.

https://github.com/lbonn/rofi

Wofi ok. Rofi-Wayland great. Tofi awesome and enough for my use case.

Natural is totally unnatural.

LC_TIME

I don’t do derivatives. Arch based distro? Just use Arch! Ubuntu, Mint, Pop or the hundreds alike, go Debian!

Rclone is awesome. Mega and PCloud got native clients that works great. Nextcloud is an alternative.

As both arch and gentoo has very good documentation, and is very standard Linux as it “always” has been, I don’t see anything hard about them. Nix is a different beast and you need to learn some new approaches.